Fig. 10.

TDNPs 2 exerted a protective effect by inactivating the NF-κB pathway. A NF-κB activity evaluation (n = 5). B Phospho-NF-κB p65 expression was evaluated by ELISA assay (n = 5). C The translocation of NF-kB-p65 to the nucleus was assessed by immunofluorescence, scale bar = 10 μm. D NF-κB-RE-Luc transgenic mice was used to investigate NF-κB activity in vivo (n = 5). E NF-κB expression in the colon was evaluated by IHC