Summary Table.

What is already known	What this study adds
•Nursing studies most often examined compliance, usability or satisfaction with the EMR system Nurses’ EMR experiences of implementation and consequences for their well-being and work satisfaction are unknown	•Measures of nurses’ work engagement, satisfaction, intention to stay, burnout and well-being worsened post-implementation of an organisation-wide EMR system The unique timing of the natural experiment captured data about nurses’ psychosocial well-being at an Australian healthcare organisation before and after an EMR implementation and experiencing the SARS-CoV-2 pandemic Strategies are needed to improve nurses’ EMR experiences and psychosocial well-being to support nurse workforce retention, productivity and quality patient care delivery Qualitative studies to explore and understand nurses’ EMR experiences can further reduce the gap in knowledge about EMR burden and workforce impacts