Table 2.

Pooled results of multivariable logistic regression of predictive factors for fatal outcome in SARS-CoV-2-infected patients suffering from chronic kidney disease

	Multivariable regression analysis on fatal outcome
	aOR	95% CI		p-value
Age
18–45 years	Reference
46–55 years	3.01	0.95	9.60	0.062
56–65 years	1.72	0.56	5.33	0.344
66–75 years	3.08	1.04	9.13	0.043
76–85 years	3.95	1.35	11.55	0.012
> 85 years	7.34	2.45	21.99	< 0.001
Gender
Female	0.87	0.66	1.15	0.340
Male	Reference
Comorbidities*
Hypertension	0.98	0.67	1.37	0.897
Chronic heart failure	1.67	1.25	2.23	< 0.001
Coronary artery disease	1.41	1.05	1.89	0.021
Diabetes mellitus type 2	0.97	0.73	1.28	0.810
COPD	1.28	0.86	1.91	0.223
Active oncological disease	1.73	1.07	2.80	0.027
Obesity	1.03	0.69	1.53	0.895
Pre-existing dialysis	1.08	0.75	1.54	0.692
Prior immunosuppressive medication*
Prior immunosuppressive medication	0.98	0.65	1.48	0.918

Multivariable logistic regression on fatal outcome was performed using the imputed data set. Obesity was defined by an indicated Body-Mass-Index > 30 kg/m². Prior immunosuppressive medication includes an interval of 3 months before SARS-CoV-2 infection, therapy limitation defined as Do-Not-Intubate-, Do-Not-Resuscitate-Orders or the refusal of intensive care, advanced respiratory support as invasive or non-invasive mechanical ventilation or ECMO. aOR: adjusted odds ratio. CI: confidence interval. COPD: chronic obstructive pulmonary disease. ECMO: extracorporeal membrane oxygenation. * No reference level indicated in binary variables