Figure 8.
Case no. 2: Transurethral resection of bladder tumor showing invasive adenocarcinoma of prostate 4 + 5 = 9/10, original magnifications 40×. IHC stain showed tumor positive for prostate markers PSA and PSMA, and negative for urothelial markers GATA-3, Uroplakin, and CK903. Neuroendocrine marker synaptophysin showed weak positive staining, considered as nonspecific and may be seen in adenocarcinomas.
Abbreviations: IHC, immunohistochemistry; PSA, prostate-specific antigen; PSMA, prostate-specific membrane antigen.