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. 2021 Dec 30;107(5):1222–1225. doi: 10.3324/haematol.2021.280239

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Figure 2. — Lymph node and bone marrow histological findings. A) Increased diffusion of histiocytes (brown color) in the bone marrow trephine biopsy; CD68 (PGM1) stain, 10X magnification; B) An histiocyte showing phagocytosis of hemopoietic elements; CD68 (PGM1) stain, 60X magnification; C) Histiocytes showing phagocytosis of red cells, platelets, erythroid precursor cells; hematoxylin-eosin stain, 60X magnification; D) A low power view of the lymph node showing paracortical necrotizing zones (N) in an otherwise preserved architecture; hematoxylin-eosin stain; E) The paracortical necrotizing areas were characterized by many reactive T lymphocytes, as shown by immunohistochemistry for CD3; 10X magnification; F) The immunostaining for CD68 revealed numerous histiocytes within the necrosis; 10X magnification.