Table 2.

Hepatoma‐derived growth factor associated with clinical measures of pulmonary arterial hypertension

	Linear regressions adjusted for age and sex
	Coefficient	Standard error	95% confidence interval		p Value
Continuous variables—Adult
6MWD (m)	−7.294	5.398	−17.887	3.298	0.177
Heart rate	1.086	0.551	0.004	2.168	0.049
Cardiac output	−0.011	0.049	−0.108	0.085	0.817
Cardiac index	0.011	0.033	−0.053	0.075	0.735
PVR	0.399	0.165	0.076	0.723	0.015
PVRI	0.559	0.13	0.305	0.813	<0.001
mPAP	0.881	0.378	0.14	1.623	0.02
mRAP	0.285	0.152	−0.014	0.583	0.062
mPCWP	−0.172	0.115	−0.398	0.053	0.135
Shunt	−2.946	1.756	−6.415	0.523	0.095
Stroke volume	−0.001	0.001	−0.003	0.001	0.392
Pulse pressure	0.481	0.412	−0.326	1.288	0.243
Pulmonary arterial compliance	−0.053	0.036	−0.123	0.017	0.141
Transpulmonary gradient	0.958	0.379	0.215	1.702	0.012
Diastolic gradient	0.721	0.305	0.124	1.318	0.018
Categorical variables
Dyspnea at rest	0.214	0.081	0.055	0.372	0.008

Note: Bold values denote statistical significance at the p < 0.05 level.

Abbreviations: 6MWD, 6‐min walk distance; mPAP, mean pulmonary artery pressure; mRAP, mean right atrial pressure; mPCWP, mean pulmonary capillary wedge pressure; PVR, pulmonary vascular resistance; PVRI, pulmonary vascular resistance index.