Table 4.
Ergospirometric and hemodynamic values according to hemodynamic impairment scores merged into three wider groups
| Score group | N pts | Peak VO2 (ml/min/kg) | Peak pulse O2 (ml) | Peak PETCO2 (mmHg) | VE/VCO2 slope | VO2/Work slope (ml/min/W) | mPAP (mmHg) | RAP (mmHg) | CI (L/min/m2) | PVR (WU) |
|---|---|---|---|---|---|---|---|---|---|---|
| A | 31 | 20.5 ± 5.3 | 10.5 ± 4.1 | 33.0 ± 4.0 | 33.3 ± 4.7 | 10.0 ± 4.1 | 38 ± 13 | 7 ± 3 | 2.6 ± 0.5 | 6.9 ± 4.3 |
| B | 72 | 15.5 ± 3.2 | 9.1 ± 3.0 | 26.5 ± 4.5 | 42.4 ± 8.5 | 10.1 ± 2.1 | 47 ± 16 | 7 ± 4 | 2.7 ± 0.7 | 8.7 ± 5.2 |
| C | 41 | 11.7 ± 2.4 | 6.9 ± 2.4 | 19.7 ± 3.0 | 60.2 ± 15.5 | 8.7 ± 2.5 | 48 ± 14 | 9 ± 5 | 2.2 ± 0.6 | 11.5 ± 6.2 |
| p for trend | <0.0001 | <0.0001 | <0.0001 | <0.0001 | 0.0531 (NS) | 0.0065 | 0.0182 | 0.0063 | 0.0004 | |
| p for ANOVA | <0.0001 | <0.0001 | <0.0001 | <0.0001 | 0.0457 | 0.0102 | 0.0066 | 0.001 | 0.0015 | |
| A versus B | <0.0001 | NS | <0.0001 | 0.0002 | NS | 0.0273 | NS | NS | NS | |
| A versus C | <0.0001 | <0.0001 | <0.0001 | <0.0001 | NS | 0.0134 | NS | 0.0376 | 0.0015 | |
| B versus C | <0.0001 | 0.0017 | <0.0001 | <0.0001 | 0.0489 | NS | 0.0058 | 0.0008 | 0.0244 | |
Note: Group A comprehends patients with scores 5, 6, and 7. Group B comprehends patients with score 8. Group C comprehends patients with scores 9 and 10. Data are expressed as absolute numbers and mean ± SD.
Abbreviations: ANOVA, analysis of variance; CI, cardiac index; mPAP, mean pulmonary arterial pressure; NS, nonsignificant; PETCO2, end‐tidal carbon dioxide pressure; pulse O2, oxygen pulse; PVR, pulmonary vascular resistance; RAP: mean right atrial pressure; VO2, oxygen uptake; VE/VCO2 slope, ventilation to carbon dioxide production slope; VO2/work, oxygen uptake to work slope.