Table 3.
Logistic regression analyses: predictive modeling for pulmonary embolism, using D‐dimer threshold of 2 mg/L
| Model 1 | Model 2 | Model 3 | Model 4 | |||||
|---|---|---|---|---|---|---|---|---|
| Predictor | Crude OR [95% CI] | P value | Adj ORa [95% CI] | P value | Adj ORa [95% CI] | P value | Adj ORa [95% CI] | P value |
| Positive D‐dimer (>2 mg/L) | 2.71 [1.11, 6.61] | 0.028* | 2.85 [1.16, 7.01] | 0.023* | 2.81 [1.14, 6.92] | 0.025* | 3.03 [1.21, 7.59] | 0.018* |
| Age (years) | ‐ | ‐ | 0.99 [0.97, 1.02] | 0.72 | 0.99 [0.97, 1.02] | 0.68 | 1.00 [0.97, 1.03] | 0.87 |
| Female | ‐ | ‐ | 0.58 [0.24, 1.42] | 0.23 | 0.55 [0.23, 1.37] | 0.20 | 0.56 [0.23, 1.40] | 0.22 |
| Black | ‐ | ‐ | 1.09 [0.46, 2.60] | 0.85 | 1.07 [0.45, 2.57] | 0.88 | 1.03 [0.43, 2.49] | 0.94 |
| BMI (kg/m2) | ‐ | ‐ | 1.00 [0.94, 1.05] | 0.89 | 0.99 [0.94, 1.05] | 0.84 | 1.00 [0.94, 1.06] | 0.96 |
| RV Dysfunction on TTE | ‐ | ‐ | ‐ | ‐ | 1.72 [0.59, 5.05] | 0.33 | ‐ | ‐ |
| Troponin (ng/mL) | ‐ | ‐ | ‐ | ‐ | ‐ | ‐ | 0.0042 [10−6, 10.35] | 0.17 |
| AUC | 0.62 | 0.66 | 0.68 | 0.71 | ||||
| Hosmer–Lemeshow GOF P value | n/ab | 0.98 | 0.94 | 0.45 | ||||
| Cross validated AUC | 0.60 | 0.52 | 0.56 | 0.59 | ||||
| AIC | 162 | 168 | 169 | 164 | ||||
Abbreviations: Adj, adjusted; AIC, akaike information criterion; AUC, area under receiver operating curve; BMI, body mass index; CI, confidence interval; GOF, goodness‐of‐fit; OR, odds ratio; RV, right ventricular; TTE, transthoracic echocardiogram.
Adjusted for variables in the respective models.
Could not calculate due to limited outcome variability.
p < 0.05.