Table 3.

Mean and standard deviation of classification accuracy (Ac), sensitivity (Se), and specificity (Sp) obtained from the random forest algorithm of the multi-dimensional marker and patient metavariable. () indicates the dimension providing the highest accuracy for each multi-dimensional marker—bold shows that log(S(i,j)) has the highest accuracy value in each classification. Clinical and radiological variables of Table 1 were classified using the same classification algorithm for the comparison.

Modality	Marker	Without SMVCCA	With SMVCCA	With ranked SMVCCA
DWIC	log(S(i,j)) Ac	0.894±0.158 (19)	0.923±0.117 (4)	0.987±0.058 (5)
	Se	1.000±0.000 (19)	1.000±0.000 (4)	0.997±0.033 (5)
	Sp	0.888±0.222 (19)	0.942±0.158 (4)	1.000±0.000 (5)
	FA	0.476±0.132 (19)	0.570±0.197 (3)	0.444±0.146 (1)
		0.718±0.215 (19)	0.748±0.269 (3)	0.661±0.279 (1)
		0.163±0.239 (19)	0.423±0.337 (3)	0.198±0.223 (1)
	AD	0.411±0.156 (19)	0.563±0.158 (5)	0.437±0.153 (3)
		0.523±0.236 (19)	0.667±0.271 (5)	0.606±0.271 (3)
		0.119±0.208 (19)	0.746±0.322 (5)	0.283±0.345 (3)
	RD	0.393±0.172 (19)	0.483±0.154 (5)	0.360±0.153 (7)
		0.468±0.275 (19)	0.532±0.247 (5)	0.626±0.337 (7)
		0.357±0.369 (19)	0.605±0.388 (5)	0.323±0.356 (7)
	ADC	0.361±0.147 (19)	0.477±0.145 (6)	0.376±0.166 (6)
		0.454±0.271 (19)	0.535±0.241 (6)	0.590±0.364 (6)
		0.186±0.259 (19)	0.607±0.377 (6)	0.449±0.441 (6)
FBA	FD	0.641±0.172 (3)	0.628±0.166 (3)	0.650±0.174 (3)
		0.881±0.184 (3)	0.844±0.206 (3)	0.871±0.205 (3)
		0.442±0.362 (3)	0.436±0.386 (3)	0.443±0.388 (3)
	FC	0.327±0.164 (3)	0.351±0.150 (2)	0.300±0.148 (3)
		0.447±0.342 (3)	0.474±0.355 (2)	0.263±0.238 (3)
		0.599±0.397 (3)	0.272±0.327 (2)	0.510±0.355 (3)
	FDC	0.601±0.156 (3)	0.517±0.153 (3)	0.477±0.160 (3)
		0.853±0.196 (3)	0.845±0.202 (3)	0.843±0.219 (3)
		0.404±0.375 (3)	0.283±0.339 (3)	0.223±0.326 (3)
Clinical variable	Sex, GA, LOS	0.179±0.112 (3)	0.183±0.127 (2)	0.333±0.156 (2)
		0.059±0.127 (3)	0.040±0.093 (2)	0.378±0.284 (2)
		0.208±0.298 (3)	0.130±0.195 (2)	0.354±0.358 (2)
Radiological variable	Intensity change and involvement on MRI	0.520±0.143 (13)	0.160±0.263 (3)	0.641±0.153 (2)
		0.111±0.274 (13)	0.147±0.307 (3)	0.630±0.315 (2)
		0.285±0.284 (13)	0.082±0.180 (3)	0.736±0.280 (2)