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. 2022 Apr 29;12:7065. doi: 10.1038/s41598-022-11045-7

Figure 2.

Figure 2

Inflammatory processes and pathways in atelectatic relative to aerated lung. (a) Functional analysis showing processes in apoptosis and immune response negatively enriched in atelectasis in LPS(−) conditions. Stress response and signaling of cAMP and HIF-1 present positive enrichment. (b) Processes and pathways related to immunity, cytokine production, stress response and MAPK cascade were positively enriched in atelectasis in LPS(+) condition. Red represents a positive normalized enrichment score. Blue represents a negative normalized enrichment score. LPS lipopolysaccharide, cAMP cyclic adenosine monophosphate, HIF hypoxia-inducible factors, MAPK mitogen-activated protein kinase.