Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Oct 5;1:35. doi: 10.1038/s43856-021-00033-z

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 1 — a Forest plot shows Mendelian randomization estimates for the causal effect of lifespan-related traits on the risk of COVID-19. Error bars show 95% confidential interval. Significant effects with FDR < 0.05 are in orange. Nominally significant effects (P < 0.05) are in black. Plots of effect sizes of all genetic instruments from GWAS for healthy aging (b), lifespan (c), and longevity (d) (x-axis) versus those for UKBB COVID-19 (y-axis); and the same set of exposure traits (e−g) (x-axis) versus HGI COVID-19 hospitalization (y-axis). Error bars represent standard errors. UKBB UK Biobank, HGI Host Genetics Initiative, pop population control, OR Odds Ratio.