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. 2021 Aug 23;1:24. doi: 10.1038/s43856-021-00025-z

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — SARS-CoV-2 viral replication events were observed in the intra-alveolar septal region (a), hyaline membranes lining the alveolar space (b), ciliated columnar respiratory epithelium of the bronchus (c), and the subepithelial sero-mucinous tracheal glands (d). Inset: a signal cluster representing viral replication. Scale bars = 200 µm in a, 100 microns in b–d. Inset scale bar = 10 µm. Arrows point to RNA-ISH signals.