Table 2.
Comparison of insulin resistance, hyperinsulinaemia and hyperhomocysteinaemia in relation to different body mass index categories
| Insulin resistance (HOMA-IR >2.5) | |||||||
|---|---|---|---|---|---|---|---|
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| Weight category | Overall | Cases | Controls | Statistical significance | |||
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| Total | IR (%) | Total | IR (%) | Total | IR (%) | χ2-test (cases vs. controls) | |
| Normal | 19 | 2 (10.5) | 9 | 2 (22.2) | 10 | 0 | χ2=2.484; P=0.115 |
| Overweight | 22 | 6 (27.3) | 10 | 5 (50.0) | 12 | 1 (8.3) | χ2=4.774; P=0.029 |
| Obese | 29 | 25 (86.2) | 16 | 16 (100) | 13 | 9 (69.2) | χ2=5.711; P=0.017 |
| Inter-BMI category statistical significance | χ2=31.47; P<0.001 | χ2=17.0; P<0.001 | χ2=16.939; P<0.001 | ||||
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| Hyperinsulinaemia | |||||||
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| Weight category | Overall | Cases | Controls | Statistical significance | |||
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| Total | Hyper insulin | Total | Hyper insulin | Total | Hyper insulin | Cases versus controls (Student’s t-test) | |
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| Normal | 19 | 0 | 9 | 0 | 10 | 0 | - |
| Overweight | 22 | 0 | 10 | 0 | 12 | 0 | - |
| Obese | 29 | 6 (20.7%) | 16 | 4 (25.0%) | 13 | 2 (15.4%) | χ2=0.404; P=0.525 |
| Inter-BMI category statistical significance | χ2=9.278; P=0.010 | χ2=5.363; P=0.068 | χ2=3.590; P=0.166 | ||||
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| Hyperhomocysteinaemia | |||||||
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| Weight category | Overall | Cases | Controls | Cases versus controls | |||
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| Total | Hyper HCy (%) | Total | Hyper HCy (%) | Total | Hyper HCy (%) | ||
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| Normal | 19 | 2 (10.5) | 9 | 1 (11.1) | 10 | 1 (10.0) | χ2=0.006; P=0.937 |
| Overweight | 22 | 10 (45.5) | 10 | 7 (70.0) | 12 | 3 (25.0) | χ2=4.455; P=0.035 |
| Obese | 29 | 17 (58.6) | 16 | 14 (87.5) | 13 | 3 (23.1) | χ2=12.272; P<0.001 |
| Inter-BMI category statistical significance | χ2=11.157; P=0.004 | χ2=14.702; P=0.001 | χ2=0.889; P=0.641 | ||||
BMI=Body mass index, HOMA-IR=Homoeostatic assessment of insulin resistance, IR=Insulin resistance