FIG. 2.

Hp(2-20)-induced chemotaxis. Hp(2-20) induces chemotactic activity in human neutrophils to a degree comparable to that of fMLF. Neutrophil transmigration after 90 min of incubation at 37°C in response to different Hp(2-20) concentrations is shown. The inset depicts the maximal level of transmigration obtained with Hp(2-20) (100 μM) and fMLF (10 nM). Data are expressed as the percentage of transmigrated cells and are given as the means + standard deviations (n = 3). The spontaneous migration was constantly about 1%.