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. 2022 Apr 29;17(4):e0266958. doi: 10.1371/journal.pone.0266958

Table 7. Estimated IgG anti-S-RBD titers of the 110 subjects that were included in both study periods by the mixed effects model using the gender and age variables as predictors.

Anti-S-RBD IgG SEM df t P
Age group (years)
21–30 (Reference) 75,481 22813.86 1.24 3.31 0.15
31–40 -45,880 11291.71 102 -4.06 p<0.001
41–50 -30,653 7756.05 102 -4.00 p<0.001
51–60 -31,296 7828.25 102 -4.00 p<0.001
61–72 -17,121 10080.61 102 -1.70 0.092
Gender
Male -14,026 5058.32 102 -2.77 0.0066
Smoking
Yes -6,879 7411.99 102 -0.93 0.35
Interaction
Smoking × Male 30,411 13716.71 102 2.22 0.024

SEM, standard error of the mean (explained variance); df, degrees of freedom; t, t-statistic, the ratio of departure of estimated from hypothesized values to standard error; P, probability of difference from zero.