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. 2022 Apr 15;9:841568. doi: 10.3389/fmed.2022.841568

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Copyright © 2022 Xu, Chen, Niu, Xing, Yang, Yin, Guo, Zhang, Qiu and Han.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The GRIP signature has prognostic significance in patients with CM. (A) ROC curve in the TCGA training cohort. (B,C) The risk scores and statuses in the TCGA training cohort. (D) PCA of the TCGA training cohort. (E) Kaplan-Meier survival curves of the high- and low-risk groups in the TCGA training cohort. (F–I) The risk signature was verified in the TCGA testing cohort. (J) Kaplan-Meier survival curve of the patients in the TCGA testing cohort. (K–O) The risk signature was verified in the TCGA entire cohort. (P–T) The GEO dataset GSE65904 was used as an external validation dataset to verify the risk signature.