Fig. 7. Interpretation of the phenomena that take place during the modified interfacial deposition. A population of micron-sized indomethacin particles in an aqueous environment is exposed to a flow of polymer and acetone. The drug particles are either broken down or dissolved due to the synergistic effect of the acetone and the polymers. The polymers are able to coat the surface of the drug NPs, making a population that can be stable due to steric interactions, while the rest of the uncoated drug particles aggregate and finally precipitate allowing removal by centrifugation.