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. 2021 Dec 30;70(Suppl 4):S511–S525. doi: 10.33549/physiolres.934744

Table 1.

A summary of the largest studies focused on metabolic interventions for AF treatment.

ARREST-AF

149 patients
Metabolic intervention: 61 patients Control group: 88
24 % reduction of AF recurrences

LEGACY

355 patients
Group 1 (10 % weight reduction) Group 2 (3–9 % weight reduction) Group 3 (<3 % weight reduction)
45 % patients without recurrence of AF 22 % without recurrence of AF 13 % without recurrence of AF

Aerobic Interval Training Reduces the Burden of Atrial Fibrillation in the Short Term

55 patients
26 patients 12-week intervention period 25 patients control group
Main time in AF reduced from 8.1 % to 4.8 % Main time in AF increased from 10.4 % to 14.6 %