Table 1.
Demographic and clinical variables | Patients treated for preference (n=12) | Patients treated for clinical progression (n=17) | Combined (n=29) | p for preference vs. progression |
---|---|---|---|---|
Age (mean ± SD) | 62.6±9.3 years | 68.2±8.3 years | 65.9±9.0 years | 0.10 |
Sex (% male) | 8 (66.7%) | 14 (82.4%) | 22 (75.9%) | 0.40 |
Initial tumor presentation size (mean ± SD) | 2.38±0.68 cm | 2.58±0.59 cm | 2.50±0.63 cm | 0.41 |
Biopsy histology | 7 clear-cell RCC (58.3%) 1 clear-cell papillary RCC (8.3%) 1 papillary type 1 (8.3%) 2 papillary type 2 (16.7%) 1 papillary NOS (8.3%) |
14 clear-cell RCC (82.4%) 1 papillary type 1 (5.9%) 1 papillary type 2 (5.9%) 1 mixed (papillary type 1, clear cell RCC; 5.9%) |
21 clear-cell RCC (72.4%) 1 clear-cell papillary RCC (3.5%) 2 papillary type 1 (6.9%) 3 papillary type 2 (10.3%) 1 mixed (papillary type 1, clear-cell RCC; 3.5%) 1 papillary NOS (3.5%) |
0.41 |
Maximum biopsy grade | 4 grade 1 (50.0%) 3 grade 2 (37.5%) 1 grade 3 (12.5%) 4 missing |
8 grade 1 (50.0%) 8 grade 2 (50.0%) 1 missing |
12 grade 1 (50.0%) 11 grade 2 (45.8%) 1 grade 3 (4.2%) 5 missing |
0.46 |
Reasons for clinical progression | N/A | 12 growth >0.5 cm/year for 2 years (70.6%) 13 absolute size >4 cm (76.5%) 8 volume doubling <1 year (47.1%)* |
N/A | N/A |
Totals exceed 100% as patients may meet more than one criterion.
NOS: not otherwise specified; RCC: renal cell carcinoma; SD: standard deviation.