Renal function effects of diet and DOCA-salt. A: urine production rate: two-way ANOVA diet P < 0.01, DOCA P < 0.01, diet × DOCA P < 0.01. B: urine osmolality: two-way ANOVA diet P = 0.25, DOCA P < 0.01, diet × DOCA P = 0.25. C: urine creatinine per day: two-way ANOVA diet P < 0.01, DOCA P < 0.01, diet × DOCA P = 0.47. D: urine Na per day: two-way ANOVA diet P = 0.90, DOCA P < 0.01, diet × DOCA P = 0.46. E: transdermal glomerular filtration rate: two-way ANOVA diet P = 0.22, DOCA P = 0.57, diet × DOCA P = 0.13. F: renal renin mRNA: two-way ANOVA diet P = 0.11, DOCA P < 0.01, diet × DOCA P < 0.01. For A–D and F, n = 8 for all groups except n = 7 for 5L0D + sham; for E, n = 10 for all groups. For A–F, data are presented as means ± SE, and *P < 0.05 by Tukey’s multiple comparisons procedure. DOCA, deoxycorticosterone acetate.