Table 2.

Tissue masses after 3 wk of DOCA-salt or sham treatment, corrected for body mass or tibia length by GLM

End Point	5L0D (n = 8, 8)	2920x (n = 8, 8)	7913 (n = 8, 8)	P Value
				Corrected model	Body mass	Tibia length	Diet	DOCA	Diet × DOCA
Interscapular fat, mg
Sham	83 ± 45	106 ± 36	112 ± 37	0.32	0.07	0.48	0.30	0.53	0.75
DOCA-salt	28 ± 38	111 ± 36	105 ± 35
Perigonadal fat, mg
Sham	224 ± 35	333 ± 32	355 ± 32	<0.01	<0.01	0.56	<0.01	<0.01	0.93
DOCA-salt	400 ± 34	485 ± 32	509 ± 31
Perirenal fat, mg
Sham	49 ± 76	83 ± 69	178 ± 69	0.79	0.53	0.39	0.90	0.40	0.34
DOCA-salt	208 ± 73	136 ± 69	106 ± 66
Inguinal fat, mg
Sham	120 ± 24	175 ± 21	173 ± 22	0.02	0.14	0.45	0.05	<0.01	0.71
DOCA-salt	180 ± 23	205 ± 22	232 ± 22
Liver, g
Sham	1.01 ± 0.09	1.06 ± 0.08	1.14 ± 0.08	<0.01	0.04	0.03	<0.01	<0.01	0.06
DOCA-salt	1.32 ± 0.09	1.80 ± 0.08	1.66 ± 0.08
Heart ventricles, mg
Sham	107 ± 3	115 ± 3	94 ± 3	<0.01	0.13	0.03	<0.01	0.68	0.02
DOCA-salt	104 ± 3	107 ± 3	102 ± 3
Adrenal glands, mg
Sham	3.9 ± 0.5	3.2 ± 0.4	2.9 ± 0.4	0.44	0.64	0.79	0.21	0.09	0.85
DOCA-salt	3.0 ± 0.4	2.6 ± 0.4	2.6 ± 0.4
Kidneys, mg
Sham	338 ± 14	329 ± 13	305 ± 13	<0.01	0.13	0.50	0.19	<0.01	0.65
DOCA-salt	424 ± 14	434 ± 13	416 ± 12
Spleen, mg
Sham	59 ± 4	68 ± 3	58 ± 3	<0.01	0.52	0.98	0.02	<0.01	0.32
DOCA-salt	46 ± 3	59 ± 3	55 ± 3

Data analyzed by GLM and presented as (EMM) ± SE after consideration of covariates at body mass = 25.44 g, tibia length = 1.86 cm. DOCA, deoxycorticosterone acetate. EMM, estimated marginal means; GLM, generalized linear model.