Table 3.
Correlations between cytokine signatures across each compartment stratified by smoking status
| Compartment Comparison | Spearman’s Coefficient | P Value |
|---|---|---|
| Nonsmokers | ||
| NLF and NELF | 0.968 | 3.50E-06 |
| NELF and sputum | 0.923 | 4.08E-06 |
| NLF and sputum | 0.879 | 2.47E-06 |
| NLF and serum | 0.735 | 1.51E-04 |
| Sputum and serum | 0.718 | 2.53E-04 |
| NELF and serum | 0.717 | 2.61E-04 |
| Cigarette smokers | ||
| NLF and NELF | 0.958 | 3.77E-06 |
| NELF and sputum | 0.916 | 3.99E-06 |
| NLF and sputum | 0.897 | 3.40E-06 |
| NLF and serum | 0.639 | 1.76E-03 |
| Sputum and serum | 0.657 | 1.19E-03 |
| NELF and serum | 0.731 | 1.68E-04 |
| E-cigarette users | ||
| NLF and NELF | 0.971 | 3.43E-06 |
| NELF and sputum | 0.918 | 4.01E-06 |
| NLF and sputum | 0.872 | 2.07E-06 |
| NLF and serum | 0.670 | 8.73E-04 |
| Sputum and serum | 0.631 | 2.08E-03 |
| NELF and serum | 0.718 | 2.53E-04 |
Correlation results are summarized as Spearman’s rank coefficients and P values for each compartment comparison. NELF, nasal epithelial lining fluid; NLF, nasal lavage fluid.