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. 2022 Feb 14;2022:8035109. doi: 10.1155/2022/8035109

Figure 1.

Figure 1

The rat CPIP model showed persistent bilateral mechanical allodynia in the hindpaw. (a) Experimental protocol for establishing the rat chronic postischemic pain (CPIP) model. (b) Representative pictures showing the rat's hindpaw during and after CPIP model establishment. The red arrow indicates the paw with the O-ring treatment (ipsilateral side). (c) Paw thickness evaluation of control and CPIP model rats of ipsilateral side. (d) 50% paw withdrawal threshold (PWT) measurement of ipsilateral hindpaw. (e) Summary of the normalized area under the curve (AUC) as in (d). (f) 50% PWT measurement of contralateral hindpaw. (g) Summary of the normalized area under the curve (AUC) as in (f). n = 6 rats/group. ∗∗p < 0.01 and ∗p < 0.05 vs. the control group.