Table 2.

Instruction for use and composition of remineralizing agents.

Material	Manufacturer	Ingredients	Instruction for use
52S4/UPGO	Experimental	Bioactive glass/synthetic polymer	Mixing ratio: 2 : 1 (powder:liquid); apply on the enamel surface for 5 min
GC tooth mousse	GC corp., Tokyo, Japan	Water, glycerol, CPP-ACP (10%), D-sorbitol, xylitol, sodium carboxymethyl cellulose, propylene glycol, silica, titanium dioxide, zinc oxide, phosphoric acid, magnesium oxide, sodium saccharin, ethyl p-hydroxybenzoate, butyl p-hydroxybenzoate, propyl p-hydroxybenzoate, and guar gum	Apply a sufficient paste on the enamel surface for 3 min.
FluoroDose®	Centrix Inc., USA	5% NaF, rosin, xylitol	Apply a thin film of varnish on the enamel surface and let the varnish dry for approximately 10 seconds.
G-BONDTM	GC Corp., Tokyo, Japan	Phosphoric acid monomer, 4-MET, UDMA, TEGDMA, photo-initiator, stabilizer, fumed silica filler, acetone, water	Apply to the enamel surface and leave undisturbed for 5–10 seconds after the end of application. Then, dry thoroughly for 5 seconds under maximum air pressure and light cure for 10 s.

CPP-ACP: casein phosphopeptide-amorphous calcium phosphate; 4-MET: 4-methacryloxyethyl trimellitic acid; TEGDMA: triethylene glycol dimethacrylate; Bis-GMA: bisphenol A-glycidyl methacrylate; UDMA: urethane dimethacrylate.