Fig. 4. Representative structure of compact (R < 0.9, see ESI† for definition) Aβ42 oligomer (remaining structures showing a minimal root-mean square deviation between their backbone structures in the 1–2 nm range are shown in Fig. S7, ESI†). Tyr, Lys and Arg side chains are emphasized in boldface. Side chains of Tyr10, Lys16, Lys28 and Arg5 with relative accessibility to water rSASA >0.3 (see ESI†) are in red, while those with rSASA <0.3 are in blue. SASA is the average value for each side chain within the pool of structures belonging to each cluster. Bond radii are arbitrary.
