Results of the cytotoxic activity of the saponin fraction and some isolated compounds from Gladiolus segetum Ker-Gawl.
| Cpd | IC50 (μg mL−1) | ||||
|---|---|---|---|---|---|
| PC-3 | HePG-2 | A-549 | MCF-7 | HCT-116 | |
| Saponin fraction | 1.13 ± 0.31 | 3.01 ± 0.36 | 1.98 ± 0.33 | 4.23 ± 0.42 | 9.77 ± 0.77 |
| 1 | 3.45 ± 0.26 | 5.98 ± 0.21 | 2.41 ± 0.34 | 6.43 ± 0.23 | >50 |
| 2 | 2.01 ± 0.23 | 6.82 ± 0.35 | 5.01 ± 0.26 | >50 | >50 |
| 3 | 10.8 ± 0.72 | 15.7 ± 0.78 | 11.5 ± 0.25 | >50 | >50 |
| 4 | 10.7 ± 0.68 | 14.4 ± 0.72 | 12.7 ± 0.58 | >50 | >50 |
| 5 | >50 | >50 | >50 | >50 | >50 |
| 6 | >50 | >50 | >50 | >50 | >50 |
| 7 | >50 | >50 | >50 | >50 | >50 |
| 8 | >50 | >50 | >50 | >50 | >50 |
| Doxorubicin | 1.63 ± 0.22 | 2.65 ± 0.32 | 1.37 ± 0.21 | 2.26 ± 0.28 | 3.86 ± 0.31 |