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. 2022 Mar 30;41(18):2638–2650. doi: 10.1038/s41388-022-02279-w

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — EHMT2 Kaplan–Meier curves of overall survival (A) and disease-free survival (B), according to the transcriptional expression in EWS patient samples (R2 Savola data). G9a Kaplan–Meier curves of overall survival (C) and disease-free survival (D), according to the protein expression in primary EWS patient samples. E Comparison of the EHMT2 mRNA level expression between primary, recurrent and metastatic EWS patient samples (R2 Savola data). F G9a expression levels in primary, recurrent and metastatic EWS patient samples. G G9a protein expression levels comparison between primary and metastatic paired EWS patient samples. Comparisons of G9a protein level of paired samples (right table). H Immunohistochemical staining of G9a in EWS paired tumor samples (20× magnifications). *p < 0.05; **p < 0.01; ***p < 0.001.