Table 1.

GC-boxes in proximal promoter regions of risk genes for SCZ, ASD, DD/ID.

	Total genes	EPD-matched genes	GC-box containing genes	GC-box gene %	Cumulative hypergeometric probability (p)	FDR-adjusted p valuea
EPD all genes (hg38)	16,455	16,455	7653	46.51
SCZ genes (SCHEMA)
p value < 1E−4	32	28	19	67.86	0.0186*	0.037*
p value < 1E−3	61	47	31	65.96	0.0056**	0.017*
SCZ genes (GWAS)
FINEMAP prioritized genes	69	63	36	57.14	0.058	0.07
All prioritized genes	643	357	184	51.54	0.0306*	0.046*
ASD genes	102	88	42	47.73	0.4503	0.45
DD/ID genes	299	258	141	54.65	0.005**	0.017*

^aFDR at the level of 0.05; * < 0.05; ** < 0.01.