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. 2021 Nov 5;27(2):929–938. doi: 10.1038/s41380-021-01318-4

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — Relative mRNA expression levels (mean ± standard error of the mean [SEM]) for Tbx1, Ng2, Pdgfr2, myelin basic protein (MBP), and myelin oligodendrocyte glycoprotein (MOG) in the fimbria (a) and corpus callosum (b) of Tbx1+/+ (n = 5) and +/− (n = 4) mice are shown. Tbx1 mRNA levels were lower in the fimbria (a, t(7) = 4.081, p = 0.0047, ***) and corpus callosum (b, t(7) = 5.221, p = 0.0012, **) of +/− mice than in those of +/+ mice. In the fimbria, levels of Ng2 (a, t(7) = 3.394, p = 0.0115, *) were lower in +/− mice than in +/+ mice. These significant differences survived Benjamini–Hochberg’s correction at the false-discovery rate (FDR) of 5%. There were no other significant differences in the fimbria or corpus callosum (a,b, p > 0.05).