Table 3.
Association of NUSAP1 expression with the clinicopathological features of BUC patients.
| Variables | N | NUSAP1 expression | p value | |||
|---|---|---|---|---|---|---|
| − | + | ++ | +++ | |||
| Total, n (%) | 178 | 40 (22.5) | 51 (28.7) | 44 (24.7) | 43 (24.1) | |
| Age (yrs) | 0.209 | |||||
| < 60 | 73 (41.0) | 20 (50.0) | 17 (33.3) | 15 (34.1) | 21 (48.8) | |
| ≥ 60 | 105 (59.0) | 20 (50.0) | 34 (66.7) | 29 (65.9) | 22 (51.2) | |
| Gender | 0.488 | |||||
| Female | 46 (25.8) | 9 (22.5) | 12 (23.5) | 10 (22.7) | 15 (34.9) | |
| Male | 132 (74.2) | 31 (77.5) | 39 (76.5) | 34 (77.3) | 28 (65.1) | |
| Tumor size (cm) | 0.017 | |||||
| < 3 | 74 (41.6) | 23 (57.5) | 22 (43.1) | 19 (43.2) | 10 (23.3) | |
| ≥ 3 | 104 (58.4) | 17 (42.5) | 29 (56.9) | 25 (56.8) | 33 (76.7) | |
| Multiplicity | 0.066 | |||||
| Single | 66 (37.1) | 22 (55.0) | 17 (33.3) | 14 (31.8) | 13 (30.2) | |
| Multiple | 112 (62.9) | 18 (45.0) | 34 (66.7) | 30 (68.2) | 30 (69.8) | |
| Tumor grade [n (%)] | 0.001 | |||||
| Low | 27 (15.2) | 14 (35.0) | 6 (11.8) | 4 (9.1) | 3 (7.0) | |
| High | 151 (67.5) | 26 (65.0) | 45 (88.2) | 40 (90.9) | 40 (93.0) | |
| Pathological stage (pT) [n (%)] | 0.027 | |||||
| T1-T2 | 61 (34.3) | 20 (50.0) | 17 (33.3) | 16 (36.4) | 8 (18.6) | |
| T3-T4 | 117 (65.7) | 20 (50.0) | 34 (66.7) | 28 (63.6) | 35 (81.4) | |
| Lymph node status | < 0.001 | |||||
| Negative | 131 (73.6) | 36 (90.0) | 43 (84.3) | 29 (65.9) | 23 (53.5) | |
| Positive | 47 (26.4) | 4 (10.0) | 8 (15.7) | 15 (34.1) | 20 (46.5) | |