Table 4.
Analysis of factors influencing lymph node metastasis in urothelial carcinoma of the bladder.
| Variables | N | Lymph node metastasis | p value | |
|---|---|---|---|---|
| Negative | Positive | |||
| Total, n (%) | 178 | 131 (73.6) | 47 (26.4) | |
| Age (yrs.) | ||||
| < 60 | 73 (41.0) | 52 (39.7) | 21 (44.7) | 0.551 |
| ≥ 60 | 105 (59.0) | 79 (60.3) | 26 (55.3) | |
| Gender | ||||
| Female | 46 (25.8) | 28 (21.4) | 18 (38.3) | 0.053 |
| Male | 132 (74.2) | 103 (78.6) | 29 (61.7) | |
| Tumor size (cm) | ||||
| < 3 | 74 (41.6) | 64 (48.9) | 10 (21.3) | 0.001 |
| ≥ 3 | 104 (58.4) | 67 (51.1) | 37 (78.7) | |
| Multiplicity | ||||
| Single | 66 (37.1) | 56 (42.7) | 10 (21.3) | 0.009 |
| Multiple | 112 (62.9) | 75 (57.3) | 37 (78.7) | |
| Tumor grade [n (%)] | ||||
| Low | 27 (15.2) | 26 (19.8) | 1 (2.1) | 0.004 |
| High | 151 (84.8) | 105 (80.2) | 46 (97.9) | |
| Pathological stage (pT) [n (%)] | ||||
| T1-T2 | 61 (34.3) | 54 (41.2) | 7 (14.9) | 0.001 |
| T3-T4 | 117 (65.7) | 77 (58.8) | 40 (85.1) | |
| NUSAP1 expression | ||||
| − | 40 (22.5) | 36 (27.5) | 4 (8.5) | < 0.001 |
| + | 51 (28.7) | 43 (32.8) | 8 (17.0) | |
| ++ | 44 (24.7) | 29 (22.1) | 15 (31.9) | |
| +++ | 43 (24.2) | 23 (17.6) | 20 (42.6) | |