Table 6.
Univariate Cox and multifactorial analysis for factors influencing 5-year-recurrence-free survival after surgery for BUC.
| Variables | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| HR (95% CI) | P value | HR (95% CI) | P value | |
| Age (yrs.; < 60 vs. ≥ 60) | 1.551 (0.924–2.604) | 0.097 | ||
| Gender (male vs. female) | 0.708 (0.427–1.176) | 0.182 | ||
| Tumor size (< 3 vs. ≥ 3) | 2.124 (1.235–3.651) | 0.006 | 1.297 (0.741–2.269) | 0.363 |
| Multiplicity (single vs. multiple) | 1.921 (1.126–3.277) | 0.017 | 1.426 (0.819–2.484) | 0.209 |
| Tumor grade (low vs. high) | 5.497 (1.724–17.525) | 0.004 | 3.066 (0.937–10.032) | 0.064 |
| pT stage (T1-T2 vs. T3-T4) | 2.913 (1.557–5.451) | 0.001 | 1.860 (0.977–3.539) | 0.059 |
| Lymph node status (negative vs. positive) | 2.562 (1.571–4.180) | < 0.001 | 1.296 (0.763–2.201) | 0.338 |
| NUSAP1 (−/+/++/+++) | 1.732 (1.381–2.170) | < 0.001 | 1.559 (1.219–1.995) | < 0.001 |