Table 7.

Univariate Cox and multifactorial analysis for factors influencing 5-year-overall survival after surgery for BUC.

Variables	Univariate analysis		Multivariate analysis
	HR (95% CI)	P value	HR (95% CI)	P value
Age (yrs.; < 60 vs. ≥ 60)	1.509 (0.863–2.638)	0.149
Gender (male vs. female)	0.683 (0.398–1.170)	0.165
Tumor size (< 3 vs. ≥ 3)	2.388 (1.306–4.366)	0.005	1.403 (0.753–2.613)	0.287
Multiplicity (single vs. multiple)	1.960 (1.099–3.495)	0.023	1.366 (0.747–2.495)	0.311
Tumor grade (low vs. high)	6.948 (1.693–28.511)	0.007	3.828 (0.910–16.105)	0.067
pT stage (T1-T2 vs. T3-T4)	3.363 (1.649–6.859)	0.001	2.105 (1.016–4.363)	0.045
Lymph node status (negative vs. positive)	2.796 (1.658–4.714)	< 0.001	1.372 (0.776–2.425)	0.277
NUSAP1 (−/+/++/+++)	1.737 (1.361–2.217)	< 0.001	1.539 (1.176–2.014)	0.002