Table 1.
Baseline patient characteristics
| All | No SHD | With SHD | p value | |
|---|---|---|---|---|
| N pts | 1417 | 613 | 804 | |
| N male pts | 965 (68.1) | 311 (50.7) | 654 (81.3) | < 0.0001 |
| Mean age (years) | 64.4 ± 16.0 | 58.0 ± 16.2 | 69.3 ± 14.0 | < 0.0001 |
| Mean BMI (kg/m2) | 27.0 ± 5.6 | 26.5 ± 6.7 | 27.4 ± 4.7 | 0.003 |
| Mean LV-EF (%) | 49.3 ± 15.7 | 61.8 ± 6.0 | 39.8 ± 14.1 | < 0.0001 |
| N pts with LV-EF < 30% | 208 (14.7) | 0 (0) | 208 (25.9) | < 0.0001 |
| Mean LVEDD (mm) | 55.4 ± 8.6 | 50.6 ± 4.8 | 59.4 ± 9.0 | < 0.0001 |
| Underlying heart disease | ||||
| None | 613 (43.3) | 613 (100) | 0 (0) | < 0.0001 |
| iCMP | 474 (33.5) | 0 (0) | 474 (59.0) | < 0.0001 |
| dCMP | 174 (12.3) | 0 (0) | 174 (21.6) | < 0.0001 |
| ARVC | 52 (3.7) | 0 (0) | 52 (6.5) | < 0.0001 |
| Other | 104 (7.3) | 0 (0) | 104 (12.9) | < 0.0001 |
| Mean GFR (ml/min) | 75.7 ± 18.4 | 84.1 ± 11.8 | 69.2 ± 19.9 | < 0.0001 |
| N pts with VT | 642 (45.3) | 179 (29.2) | 463 (57.9) | < 0.0001 |
| N pts with PVC | 610 (43.1) | 431 (70.3) | 179 (22.3) | < 0.0001 |
| N pts with ES | 165 (11.6) | 3 (0.5) | 162 (20.2) | < 0.0001 |
| N pts with ICD shock | 294 (20.8) | 6 (1.0) | 288 (35.8) | < 0.0001 |
| N pts with previous heart surgery | 206 (14.5) | 7 (1.1) | 199 (24.8) | < 0.0001 |
| N pts with aHTN | 866 (61.1) | 216 (35.2) | 650 (80.9) | < 0.0001 |
| N pts with AF | 293 (20.7) | 56 (9.1) | 237 (29.5) | < 0.0001 |
| N pts with lung disease | 137 (9.7) | 32 (5.2) | 105 (13.1) | < 0.0001 |
| N pts with PAD | 44 (3.1) | 3 (0.5) | 41 (5.1) | < 0.0001 |
| N pts on OAC | 323 (22.8) | 42 (6.9) | 281 (35.0) | < 0.0001 |
| N pts on DAPT | 105 (7.4) | 0 (0) | 105 (13.1) | < 0.0001 |
| N pts on AAD class I | 105 (7.4) | 59 (9.6) | 46 (5.7) | 0.0074 |
| N pts on AAD class III | 329 (23.2) | 27 (4.4) | 302 (37.6) | < 0.0001 |
Bold value indicates statistically signficance p < 0.05
Values are mean ± standard deviation or N (%)
SHD structural heart disease; iCMP ischemic cardiomyopathy; dCMP dilated cardiomyopathy; ARVC arrhythmogenic right ventricular cardiomyopathy; pts patients; BMI body mass index; LV-EF left ventricular ejection fraction; LVEDD left ventricular end diastolic diameter; AF atrial fibrillation; aHTN arterial hypertension; PAD peripheral artery disease; sVA sustained ventricular arrhythmia; nsVA non-sustained ventricular arrhythmia; PVC premature ventricular contraction; GFR glomerular filtration rate; ICD implantable cardioverter-defibrillator; ATP antitachycardic pacing; OAC oral anticoagulation; VKA vitamin K antagonist; NOAC novel oral anticoagulant; DAPT dual antiplatelet therapy; AAD anti-arrhythmic drug