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. 2022 Mar 16;111(5):560–573. doi: 10.1007/s00392-022-01996-2

Table 5.

Incidence rates for dabigatran- and apixaban-treated patients within the PS-trimmed cohort (A) and the PS-matched cohort (B)

Incidence rates/100 patient-years (95% CI) (A) PS-trimmed cohort (B) PS-matched cohort
Dabigatran
n = 3585
Apixaban
n = 4145
Dabigatran
n = 2683
Apixaban
n = 2683
Composite outcome* 2.35 (2.00–2.72) 2.55 (2.22–2.90) 2.55 (2.12–2.98) 2.30 (1.90–2.69)
Stroke 0.85 (0.65–1.07) 0.73 (0.56–0.90) 0.86 (0.62–1.13) 0.77 (0.54–1.02)
GI bleeding 0.35 (0.22–0.50) 0.31 (0.20–0.42) 0.41 (0.25–0.58) 0.21 (0.10–0.35)
ICH bleeding 0.18 (0.08–0.28) 0.24 (0.15–0.35) 0.17 (0.07–0.28) 0.22 (0.11–0.33)
Major bleeding 0.68 (0.50–0.86) 0.93 (0.74–1.12) 0.75 (0.53–0.98) 0.78 (0.56–1.02)
Myocardial infarction 0.42 (0.28–0.57) 0.71 (0.55–0.89) 0.45 (0.28–0.63) 0.55 (0.37–0.75)
All-cause death 2.18 (1.84–2.51) 2.71 (2.39–3.05) 2.35 (1.96–2.74) 2.56 (2.16–2.98)

PS propensity score; CI confidence interval; GI gastrointestinal; ICH intracerebral

*Composite outcome of stroke, systemic embolism, myocardial infarction, life-threatening bleeding events, and vascular death