Fig. 6. Permeation rates of INS from different nanoparticles with different microneedles. (A) Schematic of the transdermal delivery of insulin-loaded NPs using a silicon-based microneedles system and (B) effect of the length of the microneedle (L and S) on insulin permeation. Note: *P < 0.05 vs. control; **P < 0.01 vs. control.
