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. 2022 Apr 28;17(1):826–840. doi: 10.1515/med-2022-0428

Figure 1.

Figure 1

circ_0000519 level is increased in NSCLC. (a) circ_0000519 level was measured via qRT-PCR in the serum samples of NSCLC patients (n = 59) or normal subjects (n = 37). (b) circ_0000519 abundance was detected via qRT-PCR in H2170, H1299, A549, and BEAS-2B cells. (c) The information of circ_0000519 was searched from circBase. (d) circ_0000519 and GAPDH levels were measured by qRT-PCR in H2170 and A549 cells after exposure to Actinomycin D for different time points. (e) circ_0000519 and GAPDH abundances were determined via qRT-PCR in H2170 and A549 cells after the incubation of RNase R. * P < 0.05, ** P < 0.01, and *** P < 0.001.