TABLE 1.
Selected isolates of Aspergillus spp. used in this study
| Species or study isolate no. | Source no. | Provider (reference no.) |
|---|---|---|
| A. fumigatus | ||
| 1 | NCPF 7101 (AF210)ab | D. Denning (4, 5) |
| 2 | NCPF 7102 (AF294)ab | D. Denning (4) |
| 3 | NCPF 7098 (AF71)abc | D. Denning (4, 24) |
| 4 | NCPF 7097 (AF65)ab | D. Denning (4, 24) |
| 5 | NCPF 7100 (AF91)cd | D. Denning (4, 5, 24) |
| 6 | NCPF 7099 (AF72)d | D. Denning (4, 5) |
| 7 | AZ 606e | P. Verweij (NAf) |
| 8 | NIH 4215d | T. Walsh (NA) |
| 9 | A 1604ab | A. Espinel-Ingroff (10, 25) |
| A. flavus | ||
| 10 | A 1340a | A. Espinel-Ingroff (7) |
| 11 | A 830a | A. Espinel-Ingroff (7) |
| 12 | A 003ab | A. Espinel-Ingroff (7, 10, 25) |
| A. terreus | ||
| 13 | A 122a | A. Espinel-Ingroff (7) |
| 14 | NIH 961290a | T. Walsh (NA) |
| 15 | NIH 95644a | T. Walsh (NA) |
a
Low itraconazole MICs (≤1.0 μg/ml) by M38-P, Etest, or other methods described in corresponding publication(s).
b
Animals and patients responded to itraconazole treatment (isolates had low itraconazole MICs [<1.0 μg/ml]).
c
These two isolates also had either a good (isolate 3) or decreased (isolate 5) response to posaconazole in a murine model.
d
Animals and patients did not respond to itraconazole treatment (isolates had high itraconazole MICs [>8 μg/ml]).
e
Voriconazole-resistant laboratory mutant.
f
NA, not available.