TABLE 7.
Triazole MIC ranges for the reference A. flavus ATCC 204304 isolate in eight laboratories
| Antifungal agent and MIC criterion | MIC rangea
|
|||
|---|---|---|---|---|
| RPMI | RPMI-2% | M3 | M3-2% | |
| Itraconazole | ||||
| MIC-0 | 0.2–0.5 | 0.12–0.5 | 0.5–1 | 0.5–1 |
| MIC-2b | 0.06–0.2 | 0.06–0.5 | 0.06–0.2 | 0.06–0.5 |
| Posaconazole | ||||
| MIC-0 | 0.06–0.5 | 0.06–0.5 | 0.12–0.2 | 0.12 |
| MIC-2 | 0.03–0.12 | 0.03–0.06 | 0.01–0.12 | 0.03–0.06 |
| Ravuconazole | ||||
| MIC-0 | 0.5–4 | 0.5–2 | 1–4 | 0.5–4 |
| MIC-2 | 0.12–1 | 0.06–1 | 0.12–1 | 0.06–2 |
| Voriconazole | ||||
| MIC-0 | 0.5–4 | 0.5–2 | 0.5–>8 | 0.5–4 |
| MIC-2 | 0.12–0.5 | 0.06–0.5 | 0.12–1 | 0.12–2 |
a
Forty-eight-hour MICs are shown; MICs are reported in micrograms per milliliter.
b
The reference MIC-2 range is 0.12 to 0.5 μg/ml (10).