TABLE 2.
Patient no. | Pattern 69, baseline | Antiretroviral therapy | Time of follow-up (weeks) | Δ log10 HIV-1 RNA | Pattern 69, follow-up |
---|---|---|---|---|---|
3 | S-D | AZT 3TC APV | 8 | 0.25 | ND |
6 | S-SG | ABC NVP NFV SQV | 36 | −0.82 | S-ST/S |
9 | S-CA | d4T 3TC RTV SQV EFV | 40 | 0.36 | S-CA |
10 | S-VG | Megahaart | 10 | −2.26 | ND |
12 | S-SG | 2 months wash-out | 35 | −0.47 | S |
13 | S-SG | 3 months wash-out | 13 | −0.26 | ND |
15 | S-TT | ddI EFV NFV SQV | 64 | −2.06 | ND |
16 | S-SG | AZT 3TC EFV RTV SQV | 8 | 0.11 | ND |
17 | S-SA | d4T 3TC APV | 24 | 0.22 | ND |
18 | S-SS | d4T 3TC NFV | 4 | −1.01 | ND |
21 | S-ES | ABC NFV NVP | 16 | 0.48 | ND |
23 | S-SG | AZT 3TC ABC NVP SQV | 24 | −0.32 | ND |
25 | S-MT | d4T 3TC IDV | 28 | −3.19 | ND |
26 | S-ST | d4T 3TC RTV | 8 | −2.03 | ND |
29 | S-SS | d4T 3TC IDV | 28 | 0.76 | ND |
30 | S-SG | ABC SQV RTV | 22 | 1.68 | ND |
31 | S-SG | AZT 3TC RTV | 36 | −0.93 | S-SG |
47 | Insertion 5 aa | ddI ABC EFV | 24 | 0.12 | ND |
48 | Insertion 11 aa | d4T ddI NVP NFV | 24 | −0.74 | Insertion 11 aa |
52 | Deletion | d4T 3TC NFV | 24 | 0.07 | ND |
Δ log10 HIV-1 RNA, changes of the HIV plasma viral load from the baseline. Antiretroviral therapy, the drugs which were absent at baseline appear in bold (can be recycled from previous regimens). Megahaart, 8 antiretroviral drugs combined with hydroxyurea. Pattern 69, genotype at codon 69 and rearrangements. ND, genotype not determined. RTV, ritonavir; SQV, saquinavir; IDV, indinavir; NFV, nelfinavir.