The synthesis of 5-substituted 1H-tetrazoles derivatives (4a–h) via three component reaction using the CFHT nanocatalyst.

Entry	R	Product	Time (min)	Yielda (%)	Mp (°C)
					Observed	Literature
1	H	4a	40	97	170–171	168–170 (ref. 27)
2	4-NO2	4b	30	93	167–169	166–168 (ref. 27)
3	4-Br	4c	40	90	166–168	165–167 (ref. 27)
4	4-OH	4d	40	92	160–162	159–161 (ref. 28)
5	4-F	4e	30	94	178–179	176–179 (ref. 29)
6	4-OMe	4f	40	90	153–154	153–155 (ref. 30)
7	4-Me	4g	40	91	190–192	189–191 (ref. 30)
8	3-Me	4h	40	95	132–134	130–132 (ref. 30)
9	4-Cl	4i	30	92	164–166	165–168 (ref. 29)

^aThe yields relate to the isolated product.