Fig. 6. THz metamaterial biosensor for S. aureus genomic DNA detection. (A) Evaluation of the sensitivity of S. aureus genomic DNA detection. Metamaterial frequency shifts (Δf) resulting from the variation of concentrations of genomic DNA ranging from 0.05 to 10 pg μL−1. The inset shows the linear relationship between Δf and the logarithm of genomic DNA concentration. (B) Evaluation of the specificity of S. aureus genomic DNA detection: Δf produced by the genomic DNA samples from S. aureus, E. coli, A. baumannii, P. aeruginosa, Mixture 1, and Mixture 2. Mixture 1 was composed of three interfering pathogenic bacteria: E. coli, A. baumannii, and P. aeruginosa. Mixture 2 was composed of all bacterial DNA samples. Error bars indicate the standard deviation (n = 3 in all cases).
