Table 4.

Association between digital Clock Drawing Test composite scores and white matter hyperintensity volume.

dCDTa composite scoreb	White matter hyperintensity volumec				White matter hyperintensity-Larged
	Effect size	Standard error	P valuee	Effect size		Standard error	P valuee
dCDT_LMif	0.040	0.018	3.0×10−2	−0.120		0.073	1.1×10−1
dCDT_LMdf	−0.041	0.018	2.5×10−2	−0.130		0.073	8.2×10−2
dCDT_LMrf	−0.035	0.018	5.0×10−2	−0.110		0.071	1.3×10−1
dCDT_VRig	−0.042	0.019	2.3×10−2	−0.150		0.074	3.7×10−2
dCDT_VRdg	−0.043	0.019	2.0×10−2	−0.150		0.074	3.7×10−2
dCDT_VRrg	−0.043	0.019	2.2×10−2	−0.160		0.074	2.9×10−2
dCDT_PASih	−0.036	0.018	5.0×10−2	−0.100		0.073	1.5×10−1
dCDT_PASdh	−0.040	0.018	3.0×10−2	−0.130		0.073	8.0×10−2
dCDT_PASrh	−0.020	0.018	2.7×10−1	−0.035		0.073	6.3×10−1
dCDT_DSfi	−0.042	0.018	2.2×10−2	−0.160		0.072	3.0×10−2
dCDT_DSbi	−0.036	0.018	4.7×10−2	−0.100		0.072	1.5×10−1
dCDT_Trails Aj	0.037	0.018	4.4×10−2	0.160		0.073	3.1×10−2
dCDT_Trails Bj	0.039	0.018	3.4×10−2	0.150		0.074	3.6×10−2
dCDT_SIMk	−0.039	0.018	3.5×10−2	−0.130		0.073	6.6×10−2
dCDT_HVOTl	−0.040	0.019	3.4×10−2	−0.140		0.074	5.7×10−2
dCDT_BNT30m	−0.037	0.018	4.5×10−2	−0.120		0.073	9.8×10−2
dCDT_FASn	−0.041	0.018	2.5×10−2	−0.160		0.074	3.2×10−2
dCDT_FAS-Animaln	−0.035	0.018	4.8×10−2	−0.110		0.071	1.3×10−1

^adCDT: digital Clock Drawing Test.

^bThe models were adjusted for age, sex, and education.

^cThe white matter hyperintensity volume was the percentage over the total cerebral cranial volume above the tentorium and was log transformed.

^dThe large white matter hyperintensity volume was defined as that more than one standard deviation higher than the age-specific mean value.

^eBonferroni correction was used to adjust for multiple testing, and significant associations were claimed if P<.05/18 (2.8×10⁻³), where 18 is the number of tests performed.

^fWechsler Memory Scale Logical Memory—Immediate Recall (LMi), Delayed Recall (LMd), and Recognition (LMr).

^gVisual Reproduction—Immediate Recall (VRi), Delayed Recall (VRd), and Recognition (VRr).

^hPaired Associate Learning—Immediate Recall (PASi), Delayed Recall (PASd), and Recognition (PASr).

ⁱWechsler Adult Intelligence Scale Digit Span—Forward (DSf) and Backward (DSb).

^jTrail Making Test A (Trails A) and B (Trails B).

^kSIM: Similarities.

^lHVOT: Hooper Visual Organization Test.

^mBNT30: Boston Naming Test—30 item version.

ⁿVerbal fluency test (FAS and FAS-Animal).