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Fig. 1. (A) Number of proteins identified as upregulated and downregulated between ESBL-EC and non-ESBL-EC. The red bars represent the upregulated proteins. The blue bars represent the downregulated proteins. The x-axis represents the number of DEPs. The y-axis represents the fold change value. (B) Heatmap based on representative hierarchical clustering analysis with 30 DEPs between ESBL-EC and non-ESBL-EC (the detailed heatmap is shown in Fig. S1†). The relative protein level is depicted in color scale, in which red indicates upregulation, and blue indicates downregulation.