SLN formulations reported by different researchers.

Drug	Lipid	Surfactant/emulsifier	Co-Surfactant	Method for preparation of SLNs	Techniques for characterization of SLNs	Size (nm)	Ref.
Amphotericin B	Compritol® ATO 888, Precirol ATO 5 and stearic acid,	Pluronic® F-68, Pluronic® F-127,		Solvent diffusion method	DLS, DSC, zeta potential	111–415.8	37
	Compritol® ATO 888 (glycerylbehenate), glycerylpalmitostearate (Precirol® ATO 5), medium chain triglyceride	Tween 20, Pluronic® F-127, Cremophor RH40, polyoxyethylene (40) stearate (Myrj 52)		HPH	DLS, zeta potential, HPLC, TEM, FTIR, DSC, PXRD, 1H NMR	90–260	38
Baclofen	Stearic acid	Epikuron 200 (92% phosphatidylcholine)	Propionic acid, butyric acid, and sodium taurocholate	Multiple (w/o/w) warm, microemulsion	DLS	161.4	39
BuspironeHCl	Cetyl alcohol, Spermaceti	Pluronic® F-68, Tween 80		Emulsification-evaporation followed by ultrasonication	DLS	86–123	40
Camptothecin	Soybean lecithin, stearic acid	Pluronic® F-68, Tween 80	Glycerol, PEG 400, PPG	Hot HPH	TEM	196.8	41
Carvedilol	Stearic acid	Pluronic® F-68	Sodium taurocholate and ethanol	Microemulsion	TEM, DLS	120–200 and 600–800	42
Clozapine	Trimyristin, tripalmitin, tristearin, soy phosphatidylcholine	Pluronic® F-68		Ultrasonication method	DLS, zeta potential	96.7 ± 3.8 to 163.3 ± 0.7	43
Crypto-Tanshinone	Glycerylmonostearate, Compritol 888 ATO	Soy lecithin, Tween 80, sodium dehydrocholate		Ultrasonic and high-pressure homogenization method	TEM, DLS, DSC	121.4 ± 6.3 and 137.5 ± 7.1	44
Curcumin	Compritol 888 ATO	Soy lecithin, Tween 80		Microemulsion	DLS, TEM	134.6, 40–120	45
	Tristearin	Polyoxyethylene (10) stearyl ether (Brij®S10), polyoxyethylene (100) stearyl ether (Brij® S100)		Oil-in-water emulsion technique	PCS, zeta potential	111–350	45
Cyclosporine A	Imwitor® 900	Tagat®S, sodium cholate		HPH, hot HPH	DLS	157, 143	46 and 47
Diazepam	Compritol 888 ATO, Imwitor® 900	Pluronic® F-68, Tween 80		Ultrasound techniques modified high-shear homogenization and	TEM	<500	48
Doxorubicin hydrochloride	Glycerylcaprate	Polyethylene glycol 660 hydrox-ystearate (Solutol®HS15)		Ultrasonic homogenization	DLS, zeta potential, DSC	199	49
Fenofibrate	Vitamin E TPGS, Vitamin E 6–100			Hot HPH	DLS	58	50
Hydrocortisone	Precirol® ATO 5, Compritol® 888 ATO, Rylo TM MG 14 Pharma, Dynasan® 114 Dynasan® 118, Tegin® 4100	Tween 80		Hot high pressure homogenization	DLS, DSC	150–220	51
Ibuprofen	Trilaurin, tripalmitin, stearic acid	Pluronic®F127, sodium taurocholate		Solvent-free high-pressure homogenization (HPH)	DLS, X-ray powder diffraction, DSC, AFM	111–121 (empty SLN) 175–189 (loaded sample)	52
Idarubicin	Stearic acid	Epikuron 200 (soy phosphatidylcholine 95%)	Taurocholate sodium salt	Microemulsion	PCS, 90 PLUS	80 ± 10((loaded sample))	53
	Emulsifying wax	Polyoxyl 20-stearyl ether (Brij 78), D-alpha-tocopheryl polyethylene glycol succinate (vitamin E TPGS),DSPE-PEG3000	Sodium taurodeoxycholate (STDC), sodium tetradecylsulfate (STS)		PCS, Zetasizer nano Z	94.4 (blank), 80–104 (loaded sample)	54
Ketoprofen	Beeswax and carnauba wax	Tween 80, egg lecithin		Microemulsion technique	PCS, DSC	65–250 (loaded sample)	55
Lopinavir	Compritol 888 ATO (glycerylbehenate)	Pluronic®F127		Hot homogenization, ultrasonication	DLS, zeta potential, HPLC, DSC, WAXS, AFM	230	56
Lovastatin	Triglyceride, and phosphatidylcholine 95%	Pluronic®F68		Hot homogenization ultrasonication	DLS, HPLC, DSC, PXRD, LC-MS/MS	60–119	57
Methotrexate	Stearic acid, monostearin, tristearin, and Compritol 888 ATO	l-α-Soya lecithin, and Sephadex G-50		Solvent diffusion method	DLS, zeta potential, TEM	120–167	58
Nevirapine	Steric acid, Compritol 888 ATO	Dimethyldioctadecyl ammonium bromide (DODAB), Tween 80, Lecithin	1-Butanol	Microemulsion	DLS, zeta potential, field emission scanning electron microscopy (FE-SEM), DSC	153.1	59
Nitrendipine	triglyceride and phosphatidylcholine	Pluronic®F68		Hot homogenization ultrasonication method	DLS, zeta potential, scanning electron microscopy (SEM)	110–140	60
Octadecylamine-fluorescein isothiocyanate	Stearic acid	Otcadecylamine, polyethylene glycol monostearate (PEG2000-SA)		Solvent diffusion	DLS, zeta potential	203	61
Pentoxifylline	Stearic acid, cetyl alcohol, soy lecithin,	Tween 20, Pluronic F®68		Homogenization followed by the ultrasonication	DLS, zeta-potential	255–4000	62
Praziquantel	Hydrogenated castor oil	Poly vinyl alcohol (PVA)		Hot homogenization and ultrasonication	DLS, zeta-potential, SEM	344.0	63
Puerarin	Monostearin, and soy lecithin	Pluronic F®68		Solvent injection method	DLS and zeta-potential	160	64
Quercetin	Glycerylmonostearat, soy lecithin	Tween-80 and PEG 400		Emulsification-solidification	DLS, zeta-potential, TEM		65
Rifampicin	Stearic acid	PVA		Emulsion-solvent diffusion			66
Tobramycin	Stearic acid	Epikuron 200	Sodium taurocholate	Microemulsion	DLS, TEM	70–100	67
Vinpocetine	Glycerylmonostearat, soy lecithin, polyoxyethylene hydrogenated castor oil	Tween 80		Ultrasonic-solvent emulsification	DLS, TEM	70–170	68