FIG. 2.

Evolution of parasitemia in P. falciparum-infected mice before (continuous line) and after (discontinuous line) antimalarial treatment. Open symbols indicate the days of treatment. (A) Chloroquine was administered to three mice at a dose of 73 mg/kg on the first 2 days of treatment and at 36.5 mg/kg on the last day. (B) Mefloquine was administered to two mice at a dose of 50 mg/kg. (C) After failed chloroquine treatment (closed arrows) of two mice, they were treated with dihydroartemisinin (open arrows) at 50 mg/kg. (D) Quinine at 73 mg/kg was administered three times per day to two mice.