Fig. 15. Histopathological investigation of the paws of rats carried out 4 h post-inflammation induction in the different groups. The black arrows refer to the signs of inflammation (congestion, redness), thrombus formation, edema, and the appearance of inflammatory cells like mast cells and eosinophils in control non-treated, Zn–Al LDH, which were very mild in the standard group. There was the absence of inflammation signs in the levofloxacin and levofloxacin nanocomposite groups samples.