Main pharmacokinetic parameters of DHDK after tail vein injection of 14 mg kg−1 DHDK solution (n = 6)a.
Parameters | Unit | Mean | SD |
---|---|---|---|
t 1/2α | h | 0.064 | 0.021 |
t 1/2β | h | 1.79 | 0.047 |
AUC0→t | μg L−1 h | 459.47 | 193.20 |
AUC0→∞ | μg L−1 h | 534.32 | 202.71 |
V 1 | L kg−1 | 0.037 | 0.009 |
CL | L kg h−1 | 0.008 | 0.002 |
SD: standard deviation.