Main pharmacokinetic parameters of DHDK after tail vein injection of DHDK solution (mean ± SD, n = 5)a.
Parameters | Unit | Heart | Liver | Spleen | Lung | Kidney | |
---|---|---|---|---|---|---|---|
AUC0→∞ | μg L−1 h | 413.54 ± 364.13 | 2453.46 ± 424.52 | 206.81 ± 84.27 | 1627.09 ± 298.71 | 57.23 ± 32.28 | |
CL | L kg h−1 | 50.93 ± 26.52 | 5.846 ± 1.02 | 81.66 ± 45.73 | 8.89 ± 1.97 | 244.93 ± 9.95 |
SD: standard deviation.