Table 2.
CPET-derived parameters using the self-preferred and guideline-based approach in individual patients
| Patient | SPA V̇O2VAT (mL/kg/min) |
GBA V̇O2VAT (mL/kg/min) |
Number of observations V̇O2VAT (SPA; GBA) |
SPA V̇O2peak (mL/kg/min) |
GBA Valid V̇O2peaka (mL/kg/min) |
Number of observations V̇O2peak (SPA; GBA) |
SPA V̇E/V̇CO2-slope |
GBA V̇E/V̇CO2-slope |
Number of observations V̇E/V̇CO2-slope (SPA b; GBA) |
GBA OUES/kg |
Number of observations OUES (GBA) |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 11.1 ± 0.9 | 11.4 ± 0.8 | 26;25 | 15.2 ± 0.8 | 15.2 ± 0.1 | 26;26 | 24.3 ± 2.8 | 24.1 ± 1.3 | 24;26 | 17.4 (0.7) | 26 |
| 2 | 13.6 ± 3.0 | 12.9 ± 1.0 | 26;26 | 22.8 ± 1.7 | 23.2 ± 0.5 | 26;18 | 30.3 ± 1.8 | 31.2 ± 1.1 | 24;26 | 24.8 (0.1) | 26 |
| 3 | 9.6 ± 1.2 | 9.8 ± 1.4 | 22;22 | 12.7 ± 0.3 | 12.5 ± 0.1 | 26;21 | 34.2 ± 2.2 | 32.5 ± 1.0 | 22 c;26 | 16.6 (0.3) | 26 |
| 4 | 15.9 ± 2.0 | 16.3 ± 2.1 | 26;25 | 26.7 ± 0.1 | 26.5 ± 0.1 | 26;26 | 21.1 ± 2.8 | 21.3 ± 0.5 | 24;26 | 29.2 (0.4) | 26 |
| 5 | 11.8 ± 1.2 | 11.7 ± 1.1 | 26;26 | 15.7 ± 0.3 | 15.3 ± 0.3 | 26;26 | 31.6 ± 3.2 | 32.4 ± 2.3 | 24;26 | 20.4 (1.5) | 26 |
| 6 | 15.2 ± 0.8 | 15.5 ± 1.1 | 26;26 | 20.6 ± 0.2 | 20.6 ± 0.0 | 26;24 | 21.6 ± 4.3 | 21.2 ± 1.1 | 24;26 | 26.0 (2.1) | 26 |
| 7 | 8.6 ± 0.7 | 9.0 ± 0.7 | 26;26 | 11.7 ± 0.6 | 11.3 ± 0.2 | 26;18 | 34.9 ± 3.5 | 36.1 ± 2.2 | 24;26 | 14.1 (0.3) | 26 |
| 8 | 15.7 ± 0.5 | 15.9 ± 0.9 | 25;26 | 23.8 ± 0.2 | 23.5 ± 0.3 | 26;25 | 24.0 ± 2.7 | 24.4 ± 1.0 | 24;26 | 31.4 (0.7) | 26 |
| 9 | 8.6 ± 0.5 | 8.8 ± 0.5 | 26;26 | 12.0 ± 1.9 | 11.4 ± 0.1 | 26;12 | 34.2 ± 2.2 | 32.7 ± 0.3 | 24;26 | 15.9 (0.0) | 26 |
| 10 | 13.7 ± 1.6 | 13.9 ± 1.7 | 26;26 | 21.4 ± 0.1 | 21.4 ± 0.0 | 26;22 | 34.3 ± 3.1 | 34.5 ± 1.0 | 24;26 | 23.7 (0.8) | 26 |
| 11 | 10.3 ± 0.8 | 10.5 ± 0.8 | 22;22 | 12.3 ± 0.1 | 12.3 ± 0.3 | 26;8 | 45.2 ± 2.1 | 46.1 ± 0.4 | 24;26 | 12.2 (0.2) | 26 |
| 12 | 11.5 ± 1.4 | 11.5 ± 1.6 | 24;24 | 14.4 ± 0.4 | 14.3 ± 0.1 | 26;8 | 30.9 ± 1.3 | 31.1 ± 0.8 | 22 c;26 | 23.3 (0.2) | 26 |
| Grand mean | 12.1 ± 2.6 | 12.3 ± 2.6 | 25;25 | 17.4 ± 5.3 | 17.3 ± 5.4 | 26;20 | 30.7 ± 6.9 | 30.6 ± 7.1 | 24;26 | 21.6 (6.1) | 26 |
| Grand mean difference d (P-value) | −0.2 (P = 0.903) | 0.2 (P = 0.946) | 0.1 (P = 0.977) | ||||||||
Values are reported as mean ± SD
aValidity of the attained V̇O2peak based on objective criteria of a maximal effort was only determined using the guideline-based approach
bMaximum number of observations was 24, as two observers were unfamiliar with interpretation of the V̇E/V̇CO2-slope and therefore did not report this parameter
cMissing values of unknown origin
dGrand mean difference was calculated as SPA minus GBA
Abbreviations: CPET Cardiopulmonary exercise testing, GBA Guideline-based approach, OUES Oxygen uptake efficiency slope, SD Standard deviation, SPA Self-preferred approach, V̇E/V̇CO2-slope Slope of the relationship between the minute ventilation and carbon dioxide production, V̇O2peak Oxygen uptake at peak exercise, V̇O2VAT Oxygen uptake at the ventilatory anaerobic threshold